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Rush comments on commerce and the work of physicians, and on Philadelphia physicians opposed to use of mercury and bloodletting.

The diary records Rush's travel, accompanied by a servant and via horses, between the outskirts of Philadelphia and Carlisle, Pennsylvania, for an initial meeting with the trustees of Dickinson College. During the meeting the Trustees selected Dr. Charles Nisbet to serve as the College's first president. Rush described the taverns and other travel lodges at which he stopped, along with Tavern staff and other patrons, the quality of the food and drink, along with conversations he witnessed or took part in. Discussion often centered on the topics of the Constitution, paper money, as well as Dickinson College. Rush also described the results of a rapid Spring thaw on the Susquehanna River, the unusually cold weather, the scenery, and the presence whiskey stills in Irish settlements and their impact on their communities.

Contains primarily accounts for individuals the Rush's employed in their household, including various house servants, cooks, coachmen, farmers and gardeners, along with accounts for work completed by washerwomen outside the residence. Individual accounts include the servant's name, followed by notes on pay and payments made, as well as any holds on pay, advances, loans, and pay rate increases. They also indicated when an individual was supplied with shoes or clothing, or had time off to visit the country. In addition, for the majority of the individuals, Benjamin continued his habit of adding a descriptive note when the person left their service, stating the reason for the departure, commenting on the quality of that servant's work, outlining their personal and work habits (especially their drinking habits), whether they married or not, and their race or ethnic background. Includes an incomplete alphabetical index for servant names. There are a few additional household accounts briefly noted, for wood and an umbrella, as well as two receipts, one for taxes and another (laid-in) for bread.

Contains primarily Benjamin Rush's records of his expenses, including tax and bond payments, rental property fees, classes and dance lessons for family members, as well as money lent or advanced, accounts paid, cash received, and income from boarders. Rush noted the wide variety of areas where his money was spent, from postage and travel, to clothing and shoes, to household provisions and stores, along with medicines purchased. In addition, Rush created accounts for servants when they arrived, and noted their wages and any increased wages, advances, or loans; cloth, clothing, and shoes provided; with occasional notes on their personal and work habits and work history, and when they exited his service or married. Several of the comments have been redacted, along with a few pages of the account book. Finally, Rush made a few brief commonplace notes randomly in the volume, providing a "style sheet" for description of pulses, outlining a few prescriptions for patients, describing the weather, listing inventories of his furniture and linens, recording a few recipes, and in 1783, noting the news of possible peace with England.

Land deed for the Williamsburg tract purchased by Benjamin Rush, signed by Gov. Thomas Mifflin and Dep. Sec. James Trimble, with the Pennsylvania State seal, with notice that it was recorded in the state patent books.

Includes statements and receipts for medicines, advice, consultations, and sundries. In one case, Rush collected a fee on behalf of another physician. Julia Stockton Rush also served as collector, along with her husband. Includes a receipt from Richard Henderson in Leesburg, Va., for payment on the account of Mr. Carter, who had been a patient in Rush's care (see Letters series).

A copy, in an unknown hand, of a letter from Rush to Bayard regarding sentiments expressed in an earlier letter to General John Armstrong. The letter reflects post-revolutionary state politics in Pennsylvania. In the letter, Rush censures his fellow Presbyterians, who refuse to revoke the test laws and to admit amendments to the state constitution. He also condemns the taking over by the Presbyterian dominated state government of the charter of the College of Philadelphia, now the University of Pennsylvania, and refers to the College of Carlisle, or Dickinson College, established in protest to the first action. He regrets the inflammatory remarks and publications made by members of the state's single legislative body, the Council of Censors, and by Joseph Reed and Mr. Smiley, and deplores the character of Henry Osborn and Owen Faris.

Rush issued this certificate documenting that Samuel Cole attended 3 courses of his lectures on Chemistry and Pharmacy. Signed by Rush, Professor of Chemistry, College of Philadelphia.

Sworn statement that the certificate dated 1 July 1784, payable to Thomas Gilby and signed by John Pierce, is really the property of Dickinson College. signed by Benjamin Rush.