Rush briefly notes that the disease spreads, but mortality is not in proportion to the numbers afflicted. His cure is jalap and mercury, taken on the first day of the attack.
Rush notes that his pupil is better, and that he is using profuse sweating as part of his treatment for the fever. A later note was appended to the letter stating that Mrs. Rush allowed the signature to be cut away for an autograph.
David Hosack acknowledges Julia Rush's letter and states that he has sent a keepsake in memory of his wife. He requests that she consider a visit to them.