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Rush reports that only one person has been buried today in the Quaker graveyard, when 5-17 have been regular. He complains of fever treatments used by French physicians.

Rush briefly notes that the disease spreads, but mortality is not in proportion to the numbers afflicted. His cure is jalap and mercury, taken on the first day of the attack.

Rush notes that his pupil is better, and that he is using profuse sweating as part of his treatment for the fever. A later note was appended to the letter stating that Mrs. Rush allowed the signature to be cut away for an autograph.

Pickering notes that he sent Yellow Fever medicine developed by Dr. Conrad G. Bölke to the Board of Health, but is only now sending along copies of his letters from Bölke and the United States consul at Hamburg, Joseph Pitcairn, with instructions regarding the medicine's use.