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Rush announces that the publication about the fever has been well received by the citizens. He updates Julia on the condition of several patients.

Rush states that he would rejoice at news of the birth of his niece if he could, but he feels as though he will never feel joy again. The mortality this day is worse than ever. He believes it is now unsafe for her to receive articles of clothing from their house. Also, he would prefer to borrow money from her brother than from a bank at the moment.

Rush reports that the women who waited before sending for him to treat their fever have now died. His meals are now public, and he describes his diet. He notes that some doctors have been adding bark and laudanum to his new remedies. He plans to publish to expose their ignorance.

Rush expresses amazement that he remains uninfected by the fever, for he has seen over 100 patients on this date, and 40 people were buried. He states that he does not forget to treat the poor "remembering my dream in the Autumn of 1780." Many doctors have adopted his treatment, but several oppose it, as they oppose his treatment for lockjaw. He remarks that more of the French exiles have come down with the fever. He is now using bloodletting as a tool, since the weather is cooler.

Rush notes that the efficacy of his cures is now proven, and that his directions for treating and preventing the disease will be published in the newspapers. He adds that he is in surprisingly good health, since his meals now consist only of milk and vegetables, and water.

Rush writes that he is preparing for the "awful duties of the day," as yesterday exceeded any of the preceding days in distress and death, and two more physicians are ill.

Rush notes that the fever has been said to become more mild, but that is not the case, especially if his treatment has not been used. He adds that besides combatting the fever, he has to contend with the "prejudices, fears, & falsehoods" of his fellow physicians. He adds that all are tinged with infection, now. Even his own eyes are tinged a yellow color.

Rush refers to the tremendous opposition fellow physicians have given him regarding his cures, and Dr. Kuhn's publications have done the most harm. Rush announces that he has used his methods to cure his own attack of the fever.

Rush states that he is sending his assistants out to his patients, and will now visit the most serious cases. He updates her on those in the neighborhood who have not survived.

Rush seeks to reassure his wife that he is fully recovered and well cared for. He notes the numbers of those who oppose his treatments that have now left the city. He adds that it is cold, and that he hopes this will check the fever.